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Reid BJ, Li X, Galipeau PC, Vaughan TL

GLP-1 RA Trial Solutions | Signant Health The evolution of patient-reported outcomes (PROs) in early-phase oncology trials Regulatory guidance and sponsor priorities are converging to incorporate PROs into early-phase oncology trial designs, particularly as they offer critical insights into symptomatic adverse events and patient tolerability, which are vital for optimal dose determination and safety evaluation

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GRF (1-29) itself was found to suffer from rapid metabolic clearance, leading to the synthesis of analogues with substituted amino acids more resistant to enzymatic cleavage